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EMDB >EMD-
7118
Single Particle reconstruction
4.0Å
Open state structure of the full-length TRPV2 cation channel with a resolved pore turret domain
Source organism:
Rattus norvegicus
[
10116
]
Fitted atomic model:
6bo4
3Dbionotes:
available for this entry
Primary publication:
Structures of TRPV2 in distinct conformations provide insight into role of the pore turret.
Dosey TL, Wang Z, Fan G, Zhang Z, Serysheva II, Chiu W, Wensel TG.
Nat.Struct.Mol.Biol. (2019) 26 pp. 40-49
[doi:
10.1038/s41594-018-0168-8
]
PMID:
30598551
Map released:
2018-12-05
Last Modify:
2019-12-18
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Function and Biology
Experimental Information
TRPV2
Name:
TRPV2
Type:
PROTEIN
Expression system (
4932
):
Saccharomyces cerevisiae
Theoretical weight (
MDa
):
0.32
Transient receptor potential cation channel subfamily V member 2
Name:
Transient receptor potential cation channel subfamily V member 2
Type:
PROTEIN
Expression system (
4932
):
Saccharomyces cerevisiae
Theoretical weight (
MDa
):
0.08
Sample information
Sample name:
TRPV2
Proteins:
TRPV2, Transient receptor potential cation channel subfamily V member 2
Validation information
Visual analysis
Experimental information
Image processing
Number of particles:
11789
Imaging
Session
Microscope model:
FEI_POLARA_300
Electron source:
FIELD_EMISSION_GUN
Electron dose (
e/A**2
):
63.0
Holder model:
OTHER
Specimen
Preparation
Specimen concentration(
mg/ml
):
0.5
Specimen state:
PARTICLE
Vitrification
Cryogen:
ETHANE
Humidity:
98