EMDB >EMD-0103
Single Particle reconstruction 4.0Å
Source organism:
Fitted atomic model:
Primary publication:
A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses.
Abdelnabi R, Geraets JA, Ma Y, Mirabelli C, Flatt JW, Domanska A, Delang L, Jochmans D, Kumar TA, Jayaprakash V, Sinha BN, Leyssen P, Butcher SJ, Neyts J.
Plos Biol. (2019) 17 pp. e3000281-e3000281
[doi: 10.1371/journal.pbio.3000281 ]
PMID:
Map released:
2019-06-05
Last Modify:
2020-11-25

Coxsackievirus B3 (strain Nancy) [Coxsackievirus B3 (strain Nancy)]

Name:
Coxsackievirus B3 (strain Nancy)
Type:
VIRUS

Capsid protein VP1

Name:
Capsid protein VP1
Type:
PROTEIN
Theoretical weight (MDa):
0.032

Capsid protein VP2

Name:
Capsid protein VP2
Type:
PROTEIN
Theoretical weight (MDa):
0.029

Capsid protein VP3

Name:
Capsid protein VP3
Type:
PROTEIN
Theoretical weight (MDa):
0.026

Capsid protein VP4

Name:
Capsid protein VP4
Type:
PROTEIN
Theoretical weight (MDa):
0.008

4-[[4-[1,3-bis(oxidanylidene)isoindol-2-yl]phenyl]sulfonylamino]benzoic acid

Name:
4-[[4-[1,3-bis(oxidanylidene)isoindol-2-yl]phenyl]sulfonylamino]benzoic acid
Type:
LIGAND
Theoretical weight (MDa):
0.0

Sample information

Sample name:
Coxsackievirus B3 (strain Nancy)
Ligands:
4-[[4-[1,3-bis(oxidanylidene)isoindol-2-yl]phenyl]sulfonylamino]benzoic acid
Proteins:
Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, Capsid protein VP4

Validation information

Experimental information

Image processing

Number of particles:
4891

Fitting

Fitting protocol:
FLEXIBLE
Refinement space:
REAL

Imaging


Session

Microscope model:
FEI_TITAN_KRIOS
Electron source:
FIELD_EMISSION_GUN
Electron dose (e/A**2):
47.0
Holder model:
FEI_TITAN_KRIOS_AUTOGRID_HOLDER

Specimen


Preparation

Specimen state:
PARTICLE

Vitrification

Apparatus:
HOMEMADE_PLUNGER
Cryogen:
ETHANE